Nipple-sparing mastectomy preserves the nipple and areola and all the breast skin envelope around it. Only the breast tissue under the skin and nipple-areola is removed. A skin-sparing mastectomy also preserves the breast skin envelope but unlike the nipple .
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Women having a nipple-sparing mastectomy (so, keeping the entire breast skin envelope) and women with loose breast skin generally benefit from the procedure. Some findings show implant reconstruction with acellular dermal matrix may have a higher risk of complications (such as seroma (fluid collection)) compared to implant reconstruction without acellular dermal matrix [ 140,154 ].